Etodolac 300 mg cap what is it used for

Video Etodolac 300 mg cap what is it used for

drug summary & main differences | treated conditions | effectiveness | insurance coverage and cost comparison | side effects | drug interactions | warnings | frequently asked questions

No one wants to live with discomfort or pain for long periods of time, or at all. Fortunately, prescription and over-the-counter pain relievers are readily available at your nearest pharmacy. While not as potent as opioid pain relievers, which require further medical evaluation and prescription, NSAIDs such as etodolac or ibuprofen are effective in treating mild to moderate pain.

Also known as nonsteroidal anti-inflammatory drugs, NSAIDs block the production of prostaglandins. Your body may respond to certain medical conditions by producing prostaglandins, which are the chemicals responsible for pain, inflammation, and fever. NSAIDs block the prostaglandin-producing enzymes, cox-1 and cox-2, to control the body’s inflammatory response and reduce pain.

Etodolac and ibuprofen are classified as NSAIDs. however, they have some important differences.

what are the main differences between etodolac and ibuprofen?

Etodolac is sometimes known by its brand name (now discontinued), lodine. it is available as a generic drug and can only be obtained with a prescription.

etodolac has a half-life of about six to seven hours and reaches peak blood concentrations one to two hours after ingestion. It is usually taken two to three times a day for arthritis pain. There is also an extended-release etodolac tablet that has a longer half-life of about eight hours and can be taken once a day.

Ibuprofen is a more common NSAID that is available over the counter (OTC). higher concentrations of ibuprofen are also available by prescription. popular brands of ibuprofen include advil, motrin, and midol.

ibuprofen reaches peak blood levels within an hour or two after taking it. however, unlike etodolac, ibuprofen has a shorter half-life of about two hours. Prescription strength ibuprofen comes in a tablet that is usually taken three to four times a day. the otc version comes in oral tablets, capsules, and liquid suspensions.

for osteoarthritis or rheumatoid arthritis: 300 mg immediate-release two or three times a day or 400 to 500 mg twice a day. extended release 400 to 1000 mg once a day. do not exceed a maximum dose of 1200 mg per day.

for osteoarthritis or rheumatoid arthritis: 400 to 800 mg three to four times a day. do not exceed a maximum dose of 3,200 mg per day.

conditions treated with etodolac and ibuprofen

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Etodolac and ibuprofen are labeled to treat pain. They are usually taken to treat mild to moderate acute pain caused by dental procedures, migraines, or muscle aches (myalgia).

Etodolac and ibuprofen are especially useful and FDA-approved for treating the pain and inflammation of osteoarthritis and rheumatoid arthritis. higher concentrations are generally needed to treat more severe joint pain or bone pain associated with arthritis. in some cases, children over the recommended age limit may also be treated with these NSAIDs for juvenile idiopathic arthritis.

OTC ibuprofen is indicated to treat fever and menstrual cramps (primary dysmenorrhea). An injectable form of ibuprofen called neoprofen is used to treat patent ductus arteriosus (PDA), a type of heart defect, in premature babies.

Is etodolac or ibuprofen more effective?

Both etodolac and ibuprofen are effective NSAIDs for pain relief. both block cyclooxygenase (cox) enzymes to control inflammation and reduce pain in people with arthritis. however, the effects of etodolac last a little longer. therefore, some people may prefer etodolac because of its less frequent dosing.

In a double-blind study comparing etodolac and ibuprofen, 1446 patients with rheumatoid arthritis received etodolac 150 mg twice daily, etodolac 500 mg twice daily, or ibuprofen 600 mg four times daily. both doses of etodolac were found to have similar efficacy to the dose of ibuprofen. In terms of side effects, those taking etodolac experienced less indigestion, rash, and stomach bleeding than those taking ibuprofen. however, this may be related to the amounts of drug administered to patients.

Although no other clinical trials have directly compared etodolac and ibuprofen, different studies have compared other NSAIDs with etodolac or ibuprofen. a meta-analysis found that the maximum daily dose of diclofenac is more effective than the maximum daily doses of ibuprofen, naproxen, and celecoxib (but the lowest effective dose of NSAID is always recommended). another meta-analysis found that certain NSAIDs such as piroxicam and azapropazone have a high risk of toxicity, while low-dose ibuprofen has a low risk of toxicity. In general, it could be said that NSAIDs tend to differ more in safety than in effectiveness.

Because of the wide range of options for pain, it is important to consult a health care provider to learn the best treatment option. a physician or health care provider can provide appropriate medical advice for specific medical conditions.

coverage and cost comparison of etodolac versus ibuprofen

Generic etodolac tablets are generally covered by medicare and insurance plans. If you have medical conditions such as arthritis, insurance plans will likely cover etodolac for pain. The average retail cost of etodolac can vary by dosage, but you can pay about $50 per etodolac using a one-time care coupon at participating pharmacies.

Because ibuprofen is available without a prescription, some forms may not be covered by insurance plans. however, prescription strength ibuprofen tablets should be covered by most insurance plans and medicare part d depending on the treatment regimen. In general, ibuprofen is cheaper than etodolac. use a single care coupon for ibuprofen if you have a prescription from your health care provider.

common side effects of etodolac versus ibuprofen

The most common side effects of NSAIDs, including etodolac and ibuprofen, are nausea, indigestion (dyspepsia), constipation, diarrhea, and abdominal or stomach pain. Apart from gastrointestinal side effects, NSAIDs can also cause dizziness, swelling in the hands or feet (edema), headache, rash, and ringing in the ears (tinnitus). Most side effects of etodolac and ibuprofen are mild and go away on their own.

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Serious side effects of NSAIDs can include allergic reactions, such as severe rash or anaphylaxis, to the active or inactive ingredients. Other serious side effects include gastrointestinal side effects such as stomach bleeding and peptic ulcers. see your healthcare provider if you experience blood in your stool, weight loss, or severe abdominal pain.

This may not be a complete list of side effects that may occur. ask your doctor or health care provider for more information.

source: dailymed (etolac), dailymed (ibuprofen)

drug interactions between etodolac and ibuprofen

Because they block the enzyme cox-1, which plays a role in the production of platelets and blood clots, NSAIDs can interfere with the effects of anticoagulants. NSAIDs may increase the risk of bleeding from antiplatelet agents such as aspirin and anticoagulants such as warfarin.

Etodolac and ibuprofen can cause the body to retain fluid and affect kidney function. As a result, these NSAIDs can increase blood pressure. if you are also taking high blood pressure (antihypertensive) medications, such as lisinopril or losartan, you may need to monitor your blood pressure while taking an NSAID.

Etodolac and ibuprofen may affect the elimination of cyclosporine, digoxin, or methotrexate from the body. taking an NSAID might increase the risk of toxicity from cyclosporine, digoxin, or methotrexate.

find other potential drug interactions below.

Consult a healthcare professional for other possible drug interactions.

etodolac and ibuprofen warnings

Etodolac and ibuprofen, like other NSAIDs, may increase the risk of serious cardiovascular thrombotic events, such as heart attacks and strokes. such use should be avoided or monitored in people with cardiovascular problems such as heart failure, heart disease, and high blood pressure.

The use of etodolac or ibuprofen may increase the risk of serious gastrointestinal (GI) adverse events, such as stomach bleeding and peptic ulcers. Without proper treatment, inflammation and bleeding in the gastrointestinal tract can be fatal. older people may be at increased risk of serious gastrointestinal adverse events.

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NSAIDs should not be used right before or after a heart procedure called coronary artery bypass graft (CABG) surgery.

People with kidney disease may be at higher risk of further kidney problems while taking NSAIDs.

Ask your healthcare provider about other precautions before taking an NSAID.

frequently asked questions about etodolac versus ibuprofen

what is etodolac?

Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is FDA-approved to treat osteoarthritis and rheumatoid arthritis in adults. Generic etodolac can only be dispensed with a prescription.

what is ibuprofen?

ibuprofen is commonly known by brand names such as advil and motrin. It is available without a prescription to treat mild to moderate pain, fever, and menstrual cramps. Higher-strength ibuprofen is available by prescription to treat the pain and inflammation of osteoarthritis and rheumatoid arthritis.

Are etodolac and ibuprofen the same?

Etodolac and ibuprofen are not the same thing. While both are NSAIDs, they have differences in dosage and how they are used. Etodolac is a prescription medication used primarily for adults with arthritis. ibuprofen is more accessible as an over-the-counter medication for mild pain and fever.

is etodolac or ibuprofen better?

The best NSAID depends on the dose you take and what you are taking it for. Compared to ibuprofen, etodolac lasts longer in the body and therefore can be taken fewer times during the day. however, it can be more expensive than ibuprofen. Depending on your general condition, your doctor may recommend one or the other.

can i use etodolac or ibuprofen during pregnancy?

Etodolac and ibuprofen are generally not recommended during pregnancy. NSAID use during pregnancy is associated with an increased risk of birth defects or miscarriage, especially during late pregnancy. consult your health care provider if you are considering treatment options during pregnancy.

can i use etodolac or ibuprofen with alcohol?

Minimal alcohol consumption may be okay on occasion while taking an NSAID. however, drinking excessive amounts of alcohol may increase the risk of gastrointestinal adverse effects with NSAIDs. Alcohol and NSAIDs can irritate the stomach and intestinal lining, which could lead to ulcers or bleeding.

Is etodolac an analgesic?

Etodolac is an effective analgesic. it is most effective in treating pain and inflammation caused by arthritis. It is also useful for treating acute pain after certain procedures, such as dental surgery.

is etodolac stronger than naproxen?

The effectiveness of NSAIDs depends on the dose taken, among other factors. Other things being equal, etodolac and naproxen are comparable in terms of efficacy. According to double-blind studies, etodolac and naproxen are equally effective in treating rheumatoid arthritis. both drugs are also well tolerated in terms of side effects.

Content Creator Zaid Butt joined Silsala-e-Azeemia in 2004 as student of spirituality. Mr. Zahid Butt is an IT professional, his expertise include “Web/Graphic Designer, GUI, Visualizer and Web Developer” PH: +92-3217244554

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